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Just had a bit of a spook from my Brother. Ate some piel de sapo melon seeds and he said they are toxic. Are they? Should I be worried?

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I can find no evidence via internet search that the seeds of Piel de Sapo melons have any toxicity whatsoever.

Even if they did, eating a handful of seeds would be harmless. For example, while apple seeds are definitely toxic, you have to eat several dozen of them to feel any ill effects.

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Melon seeds, like pumpkin seeds, can be toasted and eaten as a snack. Recipes don't warn about a need to reach high heat, so there's no reason to think they wouldn't be safe raw. And your melon is a variety of normal melon, not something exotic to be concerned about

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